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Tianjing Li, MD, MHS, PHD +1 more instructor

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Introduction to Systematic Review and Meta-Analysis

Johns Hopkins University

About this Course

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We will introduce methods to perform systematic reviews and meta-analysis of clinical trials. We will cover how to formulate an answerable research question, define inclusion and exclusion criteria, search for the evidence, extract data, assess the risk of bias in clinical trials, and perform a meta-analysis. 
Upon successfully completing this course, participants will be able to:

- Describe the steps in conducting a systematic review
- Develop an answerable question using the “Participants Interventions Comparisons Outcomes” (PICO) framework
- Describe the process used to collect and extract data from reports of clinical trials
- Describe methods to critically assess the risk of bias of clinical trials
- Describe and interpret the results of meta-analyses

Flexible deadlines

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Shareable Certificate

Earn a Certificate upon completion

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Approx. 14 hours to complete

English

Subtitles: Arabic, French, Portuguese (European), Italian, Vietnamese, German, Russian, English, Spanish

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Flexible deadlines

Reset deadlines in accordance to your schedule.

Shareable Certificate

Earn a Certificate upon completion

100% online

Start instantly and learn at your own schedule.

Approx. 14 hours to complete

English

Subtitles: Arabic, French, Portuguese (European), Italian, Vietnamese, German, Russian, English, Spanish

Could your company benefit from training employees on in-demand skills?

Try Coursera for Business

Instructors

Instructor rating

4.74/5 (710 Ratings)

Tianjing Li, MD, MHS, PHD

Assistant Professor, Epidemiology

Bloomberg School of Public Health

123,249 Learners

1 Course

Kay Dickersin, PhD

Professor, Epidemiology

Bloomberg School of Public Health

123,249 Learners

1 Course

Offered by

Johns Hopkins University

The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.

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Syllabus - What you will learn from this course

Content Rating97%(18,144 ratings)

Week

Week 1

1 hour to complete

Introduction

To get the ball rolling, we'll take a broad overview of what to expect in this course and then introduce you to the high-level concepts of systematic review and meta-analysis and take a look at who produces and uses systematic reviews.

1 hour to complete

5 videos (Total 40 min), 3 readings

Week

Week 2

3 hours to complete

Framing the Question

In this module, we will discuss how to frame a question, as well as scope, elements, and refining the question.

3 hours to complete

7 videos (Total 73 min), 1 reading, 2 quizzes

Week

Week 3

3 hours to complete

Searching Principles and Bias Assessment

In this module we will look at finding the evidence, as well as key sources, search strategy, and assessing the risk of bias.

3 hours to complete

11 videos (Total 119 min)

11 videos

Searching Principles and Assessing Bias 2m

Lecture 3A: Finding the Evidence: Searching Principles5m

Lecture 3B: Identifying Key Sources and Techniques for Searching17m

Lecture 3C: Building a High-Quality Search Strategy17m

Lecture 3D: Documenting Your Search and Conclusions8m

Lecture 4A: Why Bias in the Individual Study is Important to a Systematic Review and Meta-Analysis7m

Lecture 4B: Selection Bias18m

Lecture 4C: Information Bias8m

Lecture 4D: Bias in the Analysis15m

Lecture 4E: Displaying Study "Quality" in Your Systematic Review16m

Byron Wallace, Phd2m

2 practice exercises

Module 330m

Module 430m

Week

Week 4

2 hours to complete

Minimizing Metabias, Qualitative Synthesis, and Interpreting Results

In this module, we will cover minimizing metabias, selection bias, information bias, how to report transparently, qualitative synthesis, and interpreting results.

2 hours to complete

9 videos (Total 88 min)

Reviews

4.8

782 reviews

5 stars
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4 stars
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3 stars
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2 stars
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1 star
0.13%

TOP REVIEWS FROM INTRODUCTION TO SYSTEMATIC REVIEW AND META-ANALYSIS

by JPAug 4, 2020

thank you very much for the opportunity to learn this subject. at least now, i will not be "left out" when my colleagues are discussing these things during critical appraisals of journals.

by PSJan 14, 2021

This course has added valuable insights to my existing understanding of systematic reviews. After completing this course, I feel more confident in my pursuit of conducting a systematic review.

by PSAug 22, 2019

Introduction to Systematic Review and Meta-Analysis course is a very good source for beginners which provides an overview on fundamental terminology and steps involved in the systematic review.

by ASJan 25, 2020

Although it is very early to say. But I can confidently say: this is one of the best thing that has happen to me this year. I am now ready to begin systematic review and meta-analysis.

View all reviews

Frequently Asked Questions

When will I have access to the lectures and assignments?
Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
The course may not offer an audit option. You can try a Free Trial instead, or apply for Financial Aid.
The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.
What will I get if I purchase the Certificate?
When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.
Is financial aid available?
Yes. In select learning programs, you can apply for financial aid or a scholarship if you can’t afford the enrollment fee. If fin aid or scholarship is available for your learning program selection, you’ll find a link to apply on the description page.

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Introduction to Systematic Review and Meta-Analysis

Introduction to Systematic Review and Meta-Analysis

About this Course